Arsenal winger Bukayo Saka has been ruled out for "many weeks" with a hamstring injury, says manager Mikel Arteta.
Trent Alexander-Arnold's passing, Morgan Rogers' dribbling and the costly absence of Mads Hermansen feature in The Debrief.
Former Premier League referee Dermot Gallagher assesses the controversial moments from the weekend's action, including Jordan Pickford's rash challenge on Malo Gusto.
Ruben Amorim claimed the anxiety around Old Trafford affected his players' mentality and admitted he faces a "big challenge" following Sunday's 3-0 defeat to Bournemouth.
Jamie Carragher believes Liverpool's 6-3 win against Tottenham was a "performance of champions".
Sonia Bompastor arrived in England with a point to prove at Chelsea. Having overseen a 16-game unbeaten run (15 wins), are the Blues as close to perfect as it gets?
Gary Neville has called for a "cultural overhaul" at Manchester United following the 3-0 defeat to Bournemouth at Old Trafford.
A defiant Ange Postecoglou once again defended Tottenham's approach and said it would not change despite shipping six goals at home to Liverpool.
Manchester City miss Rodri and cannot control counter-attacks but they now have a creativity problem too.